Comparison of multifocal electroretinogram (mfERG) measurement techniques to detect diabetic retinopathy

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The Multifocal Electroretinogram (mfERG): Applications and Limitations

What Is the mfERG? The electroretinogram (ERG) is a mass potential, the result of the summed electrical activity of the cells of the retina. Typically, the clinical ERG is elicited by full-field (Ganzfeld) flashes of light. With an appropriate selection of test and background lights, rod and cone function can be assessed separately. As the ganglion cells contribute relatively little to the full...

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Multifocal electroretinogram delays predict sites of subsequent diabetic retinopathy.

PURPOSE To examine the potential of abnormal mfERGs to predict the development of diabetic retinopathy at corresponding retinal locations 1 year later. METHODS One eye of 11 diabetic patients with nonproliferative diabetic retinopathy (NPDR) and 11 diabetic patients without retinopathy were retested 12 months after initial testing. At each time, mfERGs were recorded from 103 retinal locations...

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The multifocal pattern electroretinogram in chloroquine retinopathy.

PURPOSE Optimal screening for ocular toxicity caused by chloroquine and hydroxychloroquine is still controversial. With the multifocal pattern electroretinogram (mfPERG), a new electrophysiological technique has recently become available to detect early changes of ganglion cells. In this study this new technique is applied to a series of 10 patients seen consecutively receiving long-term chloro...

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Effect of short-term hyperglycemia on multifocal electroretinogram in diabetic patients without retinopathy.

PURPOSE To investigate the effect of variations in blood glucose level on the multifocal electroretinogram (mfERG) in patients with type 1 diabetes without retinopathy. METHODS Fourteen patients were clamped sequentially and in random order at 5 and 15 mM blood glucose for 75 minutes on the same day. MfERG was recorded in one eye at each level of blood glucose level. RESULTS Compared to eug...

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Mapping of retinal function in diabetic retinopathy using the multifocal electroretinogram.

PURPOSE To investigate focal abnormalities in the electroretinogram (ERG) signal in diabetic patients, with and without retinopathy, using a multifocal ERG. METHODS Sixteen patients with diabetes mellitus, 8 of whom had diabetic retinopathy (mean duration of diabetes: 18.5 years) and 19 approximately age-matched healthy volunteers underwent multifocal ERG testing. One hundred three retinal lo...

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ژورنال

عنوان ژورنال: Journal of Vision

سال: 2002

ISSN: 1534-7362

DOI: 10.1167/2.10.115